Guidelines regarding constitution / reconstitution of IAEC 48th Meeting of CPCSEA was held on 21st August, under the Chairmanship of Shri Hem. PDF | The effect of implementation of guidelines of the Committee for the Purpose of Control and The results showed that the implementation of CPCSEA guidelines in pharmacy institution . Mar ; J Indian Assoc Pediatr Surg. PDF | On Dec 29, , Pandey Govind and others published Guidelines of CPCSEA for conducting the experiment on animals.

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These alternatives can be substituted by demonstrations using computer-simulated learning programs. Rec Res Sci Tech. Validation, regulatory acceptance and international harmonization.

Vice Chairman and Cpscea Secretary participated in the workshop. Confusion, contradiction, and controversy. Alternatives to animal experimentation v. Humane Society Press; Network of Indian pharmacologists. Adani Port and SEZ. For this purpose, the Government has made “Breeding of and Experiments on Animals Control and Supervision Rules, ” as amended during andto regulate the guidelunes on animals.

Animal use in pharmacology education and research: The changing scenario

The in silico methods include models of diabetes, asthma and drug absorption. In the s, antibiotic cpcsda and vaccines for leprosy were developed using armadillos.

Report on Enforcement of the Animal Welfare Act. To add to this, withdrawal and ban of a number of drugs in recent years including rofecoxib, which was proven safe in animal testing highlight these legitimate concerns about extrapolation of animal test results to human beings. Howerver, it is also worthwile to consider the viewpoints that animal experiments provide an insight into the intricacies of drug action.

Poland, Czech Republic and Romania reported a relatively high level of use of computer-based alternatives. These experimental animals are mostly obtained through breeders.


The utility of toxicity tests is however debated, since many animal toxicity tests do not accurately reflect toxicity in humans, with false positive results being guideline particular problem. There have been threats to researchers from animal rights activists.

Animal use in pharmacology education and research: The changing scenario

Chitosan films, a substitute for animal and human epidermal sheets are used for in vitro permeation of polar cpcaea non-polar drugs. The terms animal testing, animal experimentation, animal research, in vivo testing and vivisection are often used interchangeably although they carry different meanings. The prevention of cruelty to animals act, as amended by Central Act 26 of The stakeholders need to provide timely information and also upgrade undergraduate and postgraduate curriculum in pharmacology, c;csea these facts into consideration.

However, they have influenced new legislations aimed at controlling the fuidelines of experimental animals and are included in the Animal Scientific Procedures Act in the United Kingdom and several similar regulations, including the CPCSEA guidelines. The MCI amendment in asked all medical colleges to use alternatives to animal experiments in the undergraduate medical course. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.

IUCN the red list of threatened species. Domagk introduced antibacterial activity of prontosil in by experiments on chicken.

Vision cocsea, Medical Council of India. All establishments engaged in research and education involving animals, are required to comply with the various guidelines, norms and stipulations set out by CPCSEA. Generation and validation of a zebrafish model of EAST epilepsy, ataxia, sensorineural deafness and tubulopathy syndrome. However, companies were allowed the sale of animal-tested products if the tests were conducted elsewhere.

Home :Committee for the Purpose of Control And Supervision of Experiments on Animals

Several students objected openly against animal dissection exercises thereafter. Table 3 Laws and regulations for use of experimental animals in India.


In India, two models are currently available: These are mechanistic models that aim to predict sensitization from mechanistic knowledge and empirical models that are 22014 at predicting from a statistical perspective. More than a cosmetic change.

New cell and tissue tests, computer models and other innovative methods can be used to replace existing animal tests. People for the ethical treatment of animals.

Acute toxicity testing of chemicals: In Silico Computer based The in silico methods include models of diabetes, asthma and drug absorption. The latter have however declined owing to the ban on use of frogs.

The use of cpcssea animal experiments is decreasing in many medical colleges across India. The mission of medicine is to eliminate suffering to maintain a good health, which may prolong the life. Typical experiments included effect of drugs on rabbit intestine, rabbit eye, central nervous system, reproductive system, as also the frog heart and frog rectus. Distillery Unit at Vill. Insulin was first isolated from dogs in and it revolutionized the treatment of diabetes.

Computer-based alternatives are being used in many countries. Indian council of medical research, New Delhi.

The upgraded versions of the earlier software programs are available but no innovative comprehensive software has been introduced so far. Plan Coordination PC Introduction. Simulated animal experiments in pharmacology. Categorising the severity of scientific procedures on animals.